拱猪

刘爱忠，博士，安徽省全椒县人，西南山地森林资源保育与利用教育部重点实验室副主任，高值木本油料新种质创制与产业化省创新团队带头人，研究员，博士生导师。长期从事在油料种子资源发掘和应用方面的研究，研究成果在国内外具有广泛的影响。在Nucleic Acids Research, Plant physiology, Journal of Cell Science, Genetics，American Journal of Botany, TAXON, BMC Genomics, Planta, Photosynthesis research，Tree genetics and genomes，PLoS One，International Journal of Molecular Sciences等国内外著名期刊发表论文80余篇，发表论文他引次数1000多次（根据Web of Sciences和researchgate 统计）。先后入选中国科拱猪 “百人计划”, “云南省海外高层次人才引进计划”和“泰山学者”。先后主持国家及省部级项目10余项。参与研究项目获云南省自然科学一等奖。工作经历：2001-2006年间，先后于美国Smithsonian研究院、Vanderbilt University从事博士后研究；2006-2008于University of Georgia大学作为研究助理教授（Research Assistant Professor）从事科研工作；2008年10月-2012.12，中国科拱猪 西双版纳热带植物园，研究员，植物分子遗传与育种课题组组长；2003年-2017年，中国科拱猪 昆明植物研究所，研究员，植物分子遗传与基因工程课题组组长；2012年至今，西南林业大学教授。目前受聘Botanical Research和Austin Cell Biology期刊编委。现任中国蓖麻工程学会理事、中国植物学民族植物学分会理事、云南省植物学会理事，云南省生物多样性和传统知识研究会执行理事长。

研究方向：

1. 木本油料种子、基因资源的发掘与利用

重点围绕具有重要经济价值的特种木本油料资源植物（如蓖麻、油茶、蒜头果和星油藤）种子累积特殊脂肪酸的生理与分子机理，着重种子在发育过程中影响或调节油脂累积（油脂含量）或脂肪酸成分生物合成的关键功能基因，通过基因修饰和表达干扰技术（如基因过表达、基因沉默等），阐明关键功能基因在储存脂类生物合成途径中的作用机理，为理解植物储存油脂累积的遗传基础提供理论依据，为旨在提高种子油含量油或脂肪酸成分的基因工程实践提供基因源和技术平台。

2. 木本资源植物的功能基因组与表观遗传研究

重点围绕具有重要经济价值的木本非木材资源（如油茶、蓖麻等），利用高通量测序技术,通过RNA-seq（转录组分析）、miRNA-seq、甲基化测序、蛋白组学等，重点解析基因组DNA甲基化对表观遗传（特别是印迹基因）和环境适应的影响机制。

科研项目：（目前承担科研项目共4项，其中：国家级3项，省（部）级1项）

1. 特种木本油料作物蓖麻高矮性状形成的遗传机理与育种应用, 国家自然科学基金（国际合作重点），2023.1-2027.12, 200万元, 在研, 主持。
2. 蓖麻从多年生木本到一年生油料作物栽培驯化过程中的遗传变异研究与种质资源发掘，国家自然科学基金（国际合作重点），2017.1-2021.12, 200万元, 已结题, 主持。
3. 星油藤种子高效累积亚麻油酸(ALA)的分子机理与基因资源发掘，国家自然科学基金（面上），2016.1-2019.12。
4. 蓖麻种子籽粒大小性状形成的遗传机理研究，国家自然科学基金（面上），2018.1-2021.12。
5. 西南林业大学高值木本油料种质新种质创制与产业化省创新团队，云南省科技创新人才计划，2018.8-2021.8, 200万元, 已结题, 主持。

近年代表性科研成果：

1. Bing Han#, Di Wu#, Yan-Yu Zhang, De-Zhu Li, Wei Xu* and Aizhong Liu*. 2022. Epigenetic regulation of seed-specific gene expression by DNA methylation valleys in castor bean. BMC Biology. 20(1): 57. (//doi.org/10.1186/s12915-02)
2. Yanyu Zhang, Yelan Li, Bing Han, Aizhong Liu and Wei Xu*. 2022. Integrated lipidomic and transcriptomic analysis reveals triacylglycerol accumulation in castor bean seedlings under heat stress. Industrial Crops & Products. 180: 114702. (//doi.org/10.1016/j.indcrop.2022.114702)
3. Shibo Wu, Di Wu, Juan Song, Yanyu , ZhangQing Tan, Tianquan Yang, Songbiao Wang*, Jianchu Xu*, Wei Xu* and Aizhong Liu*. 2022. Metabolomic and transcriptomic analyses reveal new insights into the role of abscisic acid in modulating mango fruit ripening. Horticulture Research. uhac102, //doi.org/10.1093/hr/uhac102
4. Wei Xu, Di Wu, Tianquan Yang, Chao Sun, Zaiqing Wang, Bing Han, Shibo Wu, Anmin Yu, Mark A. Chapman, Sammy Muraguri, Qing Tan, Wenbo Wang, Zhigui Bao, Aizhong Liu* and De-Zhu Li*. 2021. Genomic insights into the origin, domestication and genetic basis of agronomic traits of castor bean. Genome Biology. 22(1): 113. (//doi.org/10.1186/s13059-021-02333-y)
5. Wei Xu, Libin Zhang, Anthony B. Cunningham, Shan Li, Huifu Zhuang, Yuhua Wang* and Aizhong Liu*. 2020. Blue genome: Chromosome-scale genome reveals the evolutionary and molecular basis of indigo biosynthesis in Strobilanthes cusia. The Plant Journal. 104: 864–879. (//doi.org/10.1111/tpj.15016)
6. Bing Han, Hui Xu, Yingting Feng, Wei Xu, Qinghua Cui* and Aizhong Liu*. 2020. Genomic Characterization and Expressional Profiles of Autophagy-Related Genes (ATGs) in Oilseed Crop Castor Bean (Ricinus communis L.). International Journal of Molecular Sciences. 21(2): 562. (//doi.org/10.3390/ijms21020562)
7. Bing Han, Wei Xu, Naeem Ahmed, Anmin Yu, Zaiqing Wang and Aizhong Liu*. 2020. Changes and associations of genomic transcriptions and histone methylations with salt stress in castor bean. Plant and Cell Physiology. 61(5): pcaa037. (//doi.org/10.1093/pcp/pcaa037)
8. Sammy Muraguria, Wei Xu, Mark Chapman, Alice Muchugi, Adejobi Oluwaniyi, Oyetola Oyebanji, Aizhong Liu*. 2020. Intraspecific variation within Castor bean (Ricinus communis L.) based on chloroplast genomes. Industrial Crops and Products, 155: 112779. (//doi.org/10.1016/j.indcrop.2020.112779)
9. Wei Xu, Tianquan Yang, Lijun Qiu, Mark A. Chapman, De-Zhu Li and Aizhong Liu*. 2019. Genomic analysis reveals rich genetic variation and potential targets of selection during domestication of castor bean from perennial woody tree to annual semi-woody crop. Plant Direct. 3(10): e00173. (//doi.org/10.1002/pld3.173)
10. Anmin Yu, Fei Li, Wei Xu, Zaiqing Wang, Chao Sun, Bing Han, Yue Wang, Bo Wang, Xiaomao Cheng and Aizhong Liu*. 2019. Application of a high-resolution genetic map for chromosome-scale genome assembly and fine QTLs mapping of seed size and weight traits in castor bean. Scientific report. 9(1):11950. (//doi.org/10.1038/s41598-019-48492-8)
11. Wei Xu, Tianquan Yang, Bin Wang, Bing Han, Huangkai Zhou,Yue Wang, Dezhu Li and Aizhong Liu*. 2018. Differential expression networks and inheritance patterns of long non-coding RNAs in castor bean seeds. The Plant Journal. 95(2):324-340. (//onlinelibrary.wiley.com/doi/full/10.1111/tpj.13953)
12. Bin Wang, Yang Zhang, Haque ME, Wei Xu, Fei Li and Aizhong Liu*. 2018. Transcriptomic analyses reveal complex and interconnected sucrose signaling cascades in developing seeds of castor bean. Journal of Plant Physiology. 221:1-10. (//linkinghub.elsevier.com/retrieve/pii/S0176-1617(17)30288-2)
13. Tianquan Yang, Qian Yu, Wei Xu*, De-zhu Li, Fu Chen and Aizhong Liu*. 2018. Transcriptome analysis reveals crucial genes involved in the biosynthesis of nervonic acid in woody Malania oleifera oilseeds. BMC Plant Biology. 18(1): 247. (//doi.org/10.1186/s12870-018-1463-6)
14. Shan He, Wei Xu, Fei Li, Yue Wang and Aizhong Liu*. 2017. Intraspecific DNA methylation polymorphism in the non-edible oilseed plant castor bean. Plant Diversity. 39(5): 300-307. (//www.sciencedirect.com/science/article/pii/S2468265917300483)
15. Wei Xu#, Zexi Chen#, Naeem Ahmed, Bing Han, Qinghua Cui*, and Aizhong Liu*. 2016. Genome-Wide Identification, Evolutionary Analysis, and Stress Responses of the GRAS Gene Family in Castor Beans. International Journal of Molecular Sciences. 17(7): 1004. (//www.ncbi.nlm.nih.gov/pmc/articles/PMC4964380/pdf/ijms-17-01004.pdf)
16. Wei Xu#, Tianquan Yang#, Xue Dong, De-zhu Li, and Aizhong Liu*. 2016. Genomic DNA methylation analyses reveal the distinct profiles in castor bean seeds with persistent endosperms. Plant Physiology. 171(2): 1242-1258. (//www.plantphysiol.org/content/171/2/1242.long)
17. Nkatha Muriira, Wei Xu, Alice Muchugi, Jianchu Xu and Aizhong Liu*. 2015. De novo sequencing and assembly analysis of transcriptome in the Sodom Apple (Calotropis gigantea). BMC Genomics. 16: 723. (//bmcgenomics.biomedcentral.com/articles/10.1186/s12864-015-1908-3)
18. Wei Xu, Mengyuan Dai, Fei Li and Aizhong Liu*. 2014. Genomic imprinting, methylation and parent-of-origin effects in reciprocal hybrid endosperm of castor bean. Nucleic Acids Research. 42(11): 6987-6998. (//nar.oxfordjournals.org/content/42/11/6987.long)
19. Wei Xu, Li Fei, Lizhen Ling and Aizhong Liu*. 2013. Genome-wide survey and expression profiles of the AP2/ERF family in castor bean (Ricinus communis L.). BMC genomics. 14: 785. (//bmcgenomics.biomedcentral.com/articles/10.1186/1471-2164-14-785)
20. Zhengwei Jin, Wei Xu and Aizhong Liu*. 2013. Genomic surveys and expression analysis of bZIP gene family in castor bean (Ricinus communis L.). Planta. 239(2): 299-312. (//dx.doi.org/10.1007/s00425-013-1979-9)
21. Wei Xu, Qinghua Cui, Fei Li and Aizhong Liu*. 2013. Transcriptome-wide identification and characterization of MicroRNAs from castor bean (Ricinus communis L.). PLoS ONE, 8(7): e69995. (//journals.plos.org/plosone/article?id=10.1371/journal.pone.0069995)

招生要求：欢迎具有林学、植物学、生态学、生物学等学科背景的同学报考。

联系方式：E-mail: [email protected]；

地址：西南林业大学林学楼602室